PRESENTOR:

DR KRITHIKA CHENTHIL, FINAL YEAR POSTGRADUATE STUDENT, DEPT. OF OPHTHALMOLOGY

INSTITUTION:

SRI MANAKULA VINAYAGAR MEDICAL COLLEGE AND HOSPITAL

E-MAIL:

krithikachenthil@gmail.com

CONTACT NO:

9677109245

ADDRESS:

TYPE 1 4D MGMCRI STAFF QUARTERS, PILLAYARKUPPAM, PONDICHERY, 607402

GUIDED BY:

DR. NALLAMUTHU, PROF & HEAD OF THE DEPT. OF OPHTHALMOLOGY

TITLE:

“STUDY OF CENTRAL CORNEAL THICKNESS IN DIABETIC POPULATION”

AIM:

To study the changein Central Corneal Thickness (CCT) in Type-2 Diabetes Mellitus individuals in hyperglycemia and by following them up after 3 months

MATERIAL AND METHODS:

STUDY DESIGN:

Hospital based Analytical follow-up study

SAMPLE SIZE AND SAMPLING:

The estimated sample size was 56 derived from study done by Yesim et al using softwareopenEpiversion 3.0

RESULTS:

In our study of 56 patients’ initial HbA1c levels was in the range of 7-9 in 27 patients (48.2%), 9-11 in 15 patients (26.8%), and 11-14 in 14 patients (25%). Follow-up of patients after 3 months showed HbA1c levels <7 in 23 patients (45.1%), 7-8 in 16 patients (31.4%), and >8 in 12 patients (23.5%).

In addition, their initial FBS was 221.9 ±73.2mg/dl and follow-up FBS was 148.9 ± 41.9mg/dl whereas initial PPBS value was 306±106.4mg/dl and follow- up PPBS was 197.8±180.8mg/dl respectively which was statistically significant (p<0.05).

On analyses initial mean CCT was 552.6± 40.6 µm and mean HbA1c level of 9.4±1.9% whereas follow-up after 3 months showed a mean CCT of 548.5 ±38.0µm and mean HbA1c of 7.1 ±1.2% which was found to be statistically significant with p value of <0.001.

Our results correlated with study done by Yesim et al whose mean CCT before treatment was 552.30 ± 29.26µm with mean HbA1c of 9.36 ± 1.79% whereas after treatment mean CCT was 542.36 ± 27.20 µm with mean HbA1c of 6.45 ±0.70% after 6 months (p=0.0001)

CONCLUSION:

Our study concludes that good glycaemic control has a great impact on CCT measurements. Therefore, we should insist upon proper glycaemic control during ophthalmic check-up in diabetic patients. It is recommended to screen for central corneal thickness (CCT) in every ophthalmic examination for diabetic patients

Key words:

Diabetes, HBA1C, central corneal thickness.